Suppression of Granulopoiesis by Vesnarinone.
نویسندگان
چکیده
منابع مشابه
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Vesnarinone is a synthetic quinolinone derivative used in the treatment of cardiac failure and cancer. It is also known to cause agranulocytosis as a side effect, which restricts its use, although the mechanism underlying agranulocytosis is not well understood. Here, we show that vesnarinone binds to valosin-containing protein (VCP), which interacts with polyubiquitinated proteins and is essent...
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Vesnarinone is a synthetic quinolinone derivative used in the treatment of cardiac failure and cancer. It is also known to cause agranulocytosis as a side effect, which restricts its use, although the mechanism underlying agranulocytosis is not well understood. Here, we show that vesnarinone binds to valosin-containing protein (VCP), which interacts with polyubiquitinated proteins and is essent...
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ژورنال
عنوان ژورنال: THE JOURNAL OF THE STOMATOLOGICAL SOCIETY,JAPAN
سال: 1996
ISSN: 1884-5185,0300-9149
DOI: 10.5357/koubyou.63.8